The Familial Intracranial Aneurysm (FIA) study protocol
نویسندگان
چکیده
منابع مشابه
Genome screen to detect linkage to intracranial aneurysm susceptibility genes: the Familial Intracranial Aneurysm (FIA) study.
BACKGROUND AND PURPOSE Evidence supports a substantial genetic contribution to the risk of intracranial aneurysm (IA). The purpose of this study was to identify chromosomal regions likely to harbor genes that contribute to the risk of IA. METHODS Multiplex families having at least 2 individuals with "definite" or "probable" IA were ascertained through an international consortium. First-degree...
متن کاملSurgical Protocol and Outcome of 60 Cases With Intracranial Aneurysm
Background and Aim: This study aimed to present the results of early and delayed operation on patients with ruptured brain aneurysms. In addition to comparing the results and rates of morbidity and mortality in the surgical procedure and identifying the effective factors, this study aimed to provide methods to improve the treatment of brain aneurysm. Methods and Materials/Patients: This was a ...
متن کاملAffected twins in the familial intracranial aneurysm study.
BACKGROUND AND PURPOSE Very few cases of intracranial aneurysms (IAs) in twins have been reported. Previous work has suggested that vulnerability to IA formation is heritable. Twin studies provide an opportunity to evaluate the impact of genetics on IA characteristics, including IA location. We therefore sought to examine IA location concordance, multiplicity, and rupture status within affected...
متن کاملShould we screen for familial intracranial aneurysm?
BACKGROUND AND PURPOSE The purpose of this study was to establish whether individuals with a family history of >/=2 first-degree relatives with intracranial aneurysm should be offered screening for aneurysm. METHODS We derived 3 theoretical models and calculated the outcomes of screening with magnetic resonance angiography (MRA) followed by digital subtraction angiography (DSA) if MRA was pos...
متن کاملShould We Screen for Familial Intracranial Aneurysm?
13. ter Berg HW, Dippel DW, Limburg M, Schievink WI, van Gijn J. Familial intracranial aneurysms: a review. Stroke. 1992;23:1024–1030. 14. Lozano AM, Leblanc R. Familial intracranial aneurysms. J Neurosurg.
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ژورنال
عنوان ژورنال: BMC Medical Genetics
سال: 2005
ISSN: 1471-2350
DOI: 10.1186/1471-2350-6-17